A nerve-wracking buzz: lessons from Drosophila models of peripheral neuropathy and axon degeneration
The degeneration of axons and their terminals occurs following traumatic, toxic, or genetically-induced insults.Common molecular mechanisms unite these disparate triggers to Intermediate Pulley execute a conserved nerve degeneration cascade.In this review, we will discuss how models of peripheral nerve injury and neuropathy in Drosophila have led t